Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31601088 | 0.95 | CHRNB2 (0.38) | ALDH1A1PTPN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31601089 | 0.79 | — | — | |
| SCHEMBL31601081 | 0.74 | GAA (0.30) | GAA | |
| SCHEMBL31601070 | 0.72 | TSHR (0.31) | KMT2AHSD17B10TSHRTDP1 | |
| SCHEMBL12247923 | 0.70 | HPGD (0.51) | ALDH1A1PTPN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL18250666 | 0.68 | PTPN1 (0.43) | ALDH1A1PTPN1SMN1; SMN2RAB9AGAA | |
| SCHEMBL31601085 | 0.67 | — | — | |
| SCHEMBL4771907 | 0.67 | ALDH1A1 (0.42) | ALDH1A1PTPN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31601004 | 0.66 | — | — | |
| SCHEMBL5137967 | 0.65 | HPGD (0.41) | ALDH1A1PTPN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250170265-A1 | DIAZONIUM COMPOUNDS AND METHODS OF USE FOR DNA CLEAVAGE | NEW YORK UNIVERSITY (US) | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250170265-A1 | DIAZONIUM COMPOUNDS AND METHODS OF USE FOR DNA CLEAVAGE | OGG1, UNG, DNMT3A | ALDH1A1 1349/4885PTPN1 3624/4885SMN1; SMN2 1633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.