Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31601796 | 0.91 | THRB (0.38) | THRBMAPTPDE1BRXFP1DGAT1 | |
| SCHEMBL31601832 | 0.87 | PDE1B (0.36) | THRBMAPTPDE1BRXFP1DGAT1 | |
| SCHEMBL31602029 | 0.87 | THRB (0.39) | THRBMAPTPDE1BRXFP1DGAT1 | |
| SCHEMBL31601749 | 0.85 | NR1D1 (0.36) | PDE1BNR1D1KDM4EGAALMNA | |
| SCHEMBL31601720 | 0.83 | THRB (0.36) | THRBMAPTPDE1BRXFP1DGAT1 | |
| SCHEMBL31601743 | 0.82 | PIK3CD (0.38) | THRBMAPTRXFP1DGAT1SOAT1 | |
| SCHEMBL31601736 | 0.81 | ALDH1A1 (0.34) | MAPTPDE1BRXFP1NR1D1KDM4E | |
| SCHEMBL31601795 | 0.81 | ALDH1A1 (0.33) | PDE1BRXFP1NR1D1KDM4EGAA | |
| SCHEMBL31601920 | 0.81 | DGAT1 (0.42) | THRBMAPTPDE1BRXFP1DGAT1 | |
| SCHEMBL31601778 | 0.80 | ALDH1A1 (0.40) | THRBMAPTPDE1BRXFP1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025110815-A1 | IMIDAZO [1,2-B] PYRIDAZINE-BASED NOVEL COMPOUND AS CDK INHIBITOR AND USE THEREOF | 아이리드비엠에스 주식회사 | 2025-05-30 | — | — | WO | disclosed |