Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.56 |
| ▸ | PRKCG | P05129 | 5/20 | 0.56 |
| ▸ | PRKCB | P05771 | 5/20 | 0.56 |
| ▸ | PRKCA | P17252 | 5/20 | 0.56 |
| ▸ | PRKCH | P24723 | 5/20 | 0.56 |
| ▸ | PRKCI | P41743 | 5/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.56 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.56 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.56 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.56 |
| ▸ | PRKACA | P17612 | 2/20 | 0.56 |
| ▸ | PRKACG | P22612 | 2/20 | 0.56 |
| ▸ | PRKACB | P22694 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148480 | 1.00 | NPC1 (0.61) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL29415921 | 0.92 | PRKD3 (0.62) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL78989 | 0.92 | PRKD3 (0.62) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL3959789 | 0.90 | PRKD3 (0.61) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL6417753 | 0.81 | PRKD3 (0.56) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL3908537 | 0.81 | PRKD3 (0.59) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL1155579 | 0.80 | KDR (0.59) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL15758300 | 0.79 | PRKCB (0.64) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL12424814 | 0.78 | KDR (0.54) | NPC1RAB9APRKD3PRKCGPRKCB | |
| SCHEMBL2986726 | 0.78 | PRKD3 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122501-A1 | BENZOTHIOPHENE-3-YL- AND BENZOSELENOPHENE-3-YL (BICLYCLIC HETEROARYL) MALEMIDES AS GSK-3 INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2025-06-12 | — | — | WO | disclosed |