Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 7/20 | 0.59 |
| ▸ | PRKCG | P05129 | 7/20 | 0.59 |
| ▸ | PRKCB | P05771 | 7/20 | 0.59 |
| ▸ | PRKCA | P17252 | 7/20 | 0.59 |
| ▸ | PRKCH | P24723 | 7/20 | 0.59 |
| ▸ | PRKCI | P41743 | 7/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 7/20 | 0.59 |
| ▸ | PRKCZ | Q05513 | 7/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 7/20 | 0.59 |
| ▸ | PRKD1 | Q15139 | 7/20 | 0.59 |
| ▸ | PRKACA | P17612 | 2/20 | 0.59 |
| ▸ | PRKACG | P22612 | 2/20 | 0.59 |
| ▸ | PRKACB | P22694 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415921 | 0.88 | PRKD3 (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL78989 | 0.88 | PRKD3 (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3959789 | 0.86 | PRKD3 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL31615194 | 0.81 | NPC1 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3148480 | 0.81 | NPC1 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL6417753 | 0.81 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL12424814 | 0.78 | KDR (0.54) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL15758300 | 0.76 | PRKCB (0.64) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL2986726 | 0.75 | PRKD3 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8086286 | 0.74 | KDR (0.58) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102924437-B | 3-piperazine-4-indol maleimide compound and preparation and application thereof | UNIV DONGHUA | 2014-07-02 | — | — | CN | disclosed |
| CN-103420895-A | Preparation method of 4-aminoindole | ASCEPION PHARMACEUTICALS INC | 2013-12-04 | — | — | CN | disclosed |
| CN-102924437-A | 3-piperazine-4-indol maleimide compound and preparation and application thereof | UNIV DONGHUA | 2013-02-13 | — | — | CN | disclosed |
| JP-2009161481-A | SNAKE VENOM MYONECROSIS FACTOR INHIBITOR | INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH | 2009-07-23 | — | — | JP | disclosed |