Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | PKN1 | Q16512 | 4/20 | 0.60 |
| ▸ | PKN2 | Q16513 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RHEB | Q15382 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719495 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4EPKN1PKN2NPC1 | |
| SCHEMBL5885447 | 0.85 | NPC1 (0.62) | ALDH1A1KDM4EPKN1PKN2NPC1 | |
| SCHEMBL29002247 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL695531 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL5542508 | 0.80 | ALDH1A1 (0.37) | ALDH1A1KDM4EPKN1PKN2NPC1 | |
| SCHEMBL695990 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EPKN1PKN2NPC1 | |
| SCHEMBL29693614 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EPKN1PKN2NPC1 | |
| SCHEMBL700482 | 0.74 | GAA (0.51) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| Ridinilazole SCHEMBL29785777 | 0.74 | NPC1 (0.73) | ALDH1A1KDM4EPKN1PKN2NPC1 | |
| Ridinilazole SCHEMBL29613225 | 0.74 | NPC1 (0.73) | ALDH1A1KDM4EPKN1PKN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093400-B2 | Compounds useful in therapy | PFIZER INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100317652-A1 | Compounds Useful In Therapy | PFIZER INC | 2010-12-16 | — | — | US | disclosed |
| US-7745630-B2 | Triazolyl piperidine arginine vasopressin receptor modulators | BRYANS JUSTIN STEPHEN | 2010-06-29 | — | — | US | disclosed |
| US-20050154024-A1 | Compounds useful in therapy | PFIZER INC | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154024-A1 | Compounds useful in therapy | PTGER4, PTGER3, ALOX5 | ALDH1A1 2650/4885KDM4E 3377/4885PKN1 4437/4885 |
| US-20100317652-A1 | Compounds Useful In Therapy | AVPR1A, AVPR1B, AVPR2 | ALDH1A1 2031/4885KDM4E 954/4885PKN1 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.