Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26927708 | 0.91 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA | |
| SCHEMBL31622905 | 0.84 | KDM4E (0.37) | CYP3A4SLC6A4ALDH1A1LMNATP53 | |
| SCHEMBL17793566 | 0.83 | SLC6A4 (0.46) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA | |
| SCHEMBL17793530 | 0.83 | SLC6A4 (0.46) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA | |
| SCHEMBL17793531 | 0.83 | SLC6A4 (0.46) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA | |
| SCHEMBL17793574 | 0.82 | SLC6A4 (0.37) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA | |
| SCHEMBL19627194 | 0.79 | CYP1A2 (0.32) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA | |
| SCHEMBL19627113 | 0.78 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA | |
| SCHEMBL17793521 | 0.78 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA | |
| SCHEMBL19630899 | 0.78 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C19SLC6A4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197395-A1 | IBOGAINE AND NORIBOGAINE ANALOGS AND USES THEREOF | ATAI THERAPEUTICS INC (US) | 2025-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197395-A1 | IBOGAINE AND NORIBOGAINE ANALOGS AND USES THEREOF | OPRM1, OPRK1, OPRD1 | CYP1A2 144/4885CYP3A4 297/4885CYP2C19 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.