Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31622901 | 0.84 | CYP1A2 (0.37) | ALDH1A1SMN1; SMN2SLC6A4LMNATP53 | |
| SCHEMBL19630845 | 0.83 | SLC6A4 (0.48) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL19630824 | 0.83 | SLC6A4 (0.48) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL31291663 | 0.80 | SLC6A4 (0.48) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL31622904 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL19630751 | 0.79 | SIGMAR1 (0.34) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL31291619 | 0.78 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL19630816 | 0.77 | SLC6A4 (0.45) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL26927708 | 0.76 | CYP1A2 (0.36) | ALDH1A1SMN1; SMN2SLC6A4LMNATP53 | |
| SCHEMBL26326406 | 0.74 | SLC6A4 (0.40) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197395-A1 | IBOGAINE AND NORIBOGAINE ANALOGS AND USES THEREOF | ATAI THERAPEUTICS INC (US) | 2025-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197395-A1 | IBOGAINE AND NORIBOGAINE ANALOGS AND USES THEREOF | OPRM1, OPRK1, OPRD1 | KDM4E 3785/4885ALDH1A1 349/4885HPGD 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.