Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449040 | 0.80 | PDE10A (0.41) | NR3C1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL3167522 | 0.77 | HDAC1 (0.48) | KMT2AMEN1TRPV1 | |
| SCHEMBL2062047 | 0.74 | L3MBTL1 (0.43) | KMT2A | |
| SCHEMBL2061275 | 0.71 | ALOX15 (0.51) | — | |
| SCHEMBL14777001 | 0.71 | KMT2A (0.41) | KMT2AMEN1CYP3A4TRPV1 | |
| SCHEMBL15630973 | 0.70 | KEAP1 (0.49) | KMT2AMEN1 | |
| SCHEMBL3168762 | 0.70 | KMT2A (0.40) | KMT2AMEN1TRPV1 | |
| SCHEMBL1292923 | 0.69 | GAA (0.67) | KMT2AMEN1 | |
| SCHEMBL21991498 | 0.68 | KMT2A (0.41) | KMT2ACYP1A2LMNA | |
| SCHEMBL13452498 | 0.67 | ALDH1A1 (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995241-B1 | Inhibitors of ion channels | ICAGEN INC (US) | 2010-03-17 | — | — | EP | disclosed |
| EP-1995241-A1 | Inhibitors of ion channels | ICAgen, Incorporated (US) | 2008-11-26 | — | — | EP | disclosed |