Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16217689 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KMT2APLAUSMN1; SMN2LMNA | |
| SCHEMBL4667940 | 0.67 | ESR1 (0.37) | ALDH1A1KDM4EKMT2APLAUMEN1 | |
| SCHEMBL16217691 | 0.67 | ESR1 (0.34) | ALDH1A1HPGDSMN1; SMN2LMNAHTT | |
| Ammonia Solution, Strong SCHEMBL4908574 | 0.66 | ESR1 (0.36) | ALDH1A1KDM4EKMT2APLAUMEN1 | |
| SCHEMBL18704077 | 0.66 | RECQL (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL22833378 | 0.66 | MGLL (0.36) | ALDH1A1KDM4EHPGDKMT2ARAD52 | |
| SCHEMBL24076866 | 0.66 | KMT2A (0.35) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL19621808 | 0.65 | ESR1 (0.35) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL2614944 | 0.64 | RECQL (0.35) | KMT2AHTTGAA | |
| SCHEMBL24225498 | 0.64 | NUDT1 (0.34) | KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |