Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634665 | 0.82 | UCHL1 (0.44) | POLBKDM4EUCHL1NPC1L3MBTL1 | |
| SCHEMBL30458036 | 0.81 | MC4R (0.57) | MC4R | |
| SCHEMBL30833316 | 0.81 | MC4R (0.57) | MC4R | |
| SCHEMBL31634675 | 0.80 | GRM5 (0.46) | POLBKDM4EHCRTR1UCHL1NPC1 | |
| SCHEMBL28534357 | 0.79 | GPR119 (0.48) | POLBKDM4EHCRTR2UCHL1 | |
| SCHEMBL30948988 | 0.78 | USP30 (0.43) | POLBHCRTR1HCRTR2MC4R | |
| SCHEMBL31634709 | 0.75 | MC4R (0.40) | POLBMC4R | |
| SCHEMBL29091778 | 0.75 | GPR119 (0.46) | POLBKDM4EUCHL1NPC1LMNA | |
| SCHEMBL28505082 | 0.74 | POLB (0.47) | POLBKDM4ENPC1L3MBTL1LMNA | |
| SCHEMBL28505081 | 0.74 | POLB (0.47) | POLBKDM4ENPC1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |