Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28714099 | 0.84 | LMNA (0.61) | NPSR1LMNAUSP30L3MBTL1KDM4E | |
| SCHEMBL18591288 | 0.84 | LMNA (0.61) | NPSR1LMNAUSP30L3MBTL1KDM4E | |
| SCHEMBL29841015 | 0.84 | LMNA (0.61) | NPSR1LMNAUSP30L3MBTL1KDM4E | |
| SCHEMBL31634665 | 0.82 | UCHL1 (0.44) | NPSR1LMNAUSP30L3MBTL1KDM4E | |
| SCHEMBL16136237 | 0.80 | ALDH1A1 (0.56) | GRM5USP30L3MBTL1NPC1MAPT | |
| SCHEMBL28534357 | 0.80 | GPR119 (0.48) | KDM4EPOLBUCHL1 | |
| SCHEMBL31634692 | 0.80 | POLB (0.43) | NPSR1LMNAL3MBTL1KDM4EPOLB | |
| SCHEMBL18562254 | 0.79 | LMNA (0.52) | GRM5NPSR1LMNAUSP30L3MBTL1 | |
| SCHEMBL18561456 | 0.79 | LMNA (0.52) | GRM5NPSR1LMNAUSP30L3MBTL1 | |
| SCHEMBL30948964 | 0.78 | USP30 (0.53) | USP30L3MBTL1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |