SCHEMBL31635533

SCHEMBL31635533

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)CNC(=O)c2ccc(F)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PRKAA2 P54646 3/20 0.43
▸ CD274 Q9NZQ7 2/20 0.41
▸ EPHX2 P34913 1/20 0.39
▸ TP53 P04637 1/20 0.38
▸ KDM1A O60341 1/20 0.37
▸ HDAC1 Q13547 1/20 0.37
▸ EGLN1 Q9GZT9 6/20 0.37
▸ PREP P48147 1/20 0.37
▸ USP30 Q70CQ3 1/20 0.36
▸ ROCK2 O75116 1/20 0.36
▸ MKNK1 Q9BUB5 1/20 0.36
▸ MKNK2 Q9HBH9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774812 0.85 CYP11B2 (0.42) PRKAA2KDM1AEGLN1MKNK1MKNK2
SCHEMBL30773967 0.85 NAAA (0.40) PRKAA2KDM1A
SCHEMBL30774003 0.83 NAAA (0.44) PRKAA2
SCHEMBL30774857 0.81 SLC22A12 (0.40) KDM1AEGLN1USP30
SCHEMBL30774875 0.80 SLC22A12 (0.39) CD274EGLN1USP30
SCHEMBL30774747 0.80 SLC22A12 (0.39) USP30
SCHEMBL30774559 0.79 USP30 (0.41) PRKAA2KDM1AEGLN1USP30MKNK1
SCHEMBL30773988 0.78 NAAA (0.40) USP30
SCHEMBL30773968 0.78 KDM1A (0.44) EPHX2KDM1AEGLN1MKNK1MKNK2
SCHEMBL30774594 0.77 STAT3 (0.42) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 PRKAA2 1880/4885CD274 4712/4885EPHX2 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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