SCHEMBL30773968

SCHEMBL30773968

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 2/20 0.44
▸ STAT3 P40763 2/20 0.44
▸ KCNH2 Q12809 3/20 0.40
▸ EPHX2 P34913 1/20 0.40
▸ KIF11 P52732 1/20 0.39
▸ EGLN1 Q9GZT9 1/20 0.38
▸ SLC22A12 Q96S37 1/20 0.38
▸ CETP P11597 1/20 0.38
▸ SCN5A Q14524 1/20 0.38
▸ SCN9A Q15858 1/20 0.38
▸ VNN1 O95497 1/20 0.37
▸ MAOB P27338 1/20 0.36
▸ PTGDR2 Q9Y5Y4 1/20 0.36
▸ EIF4E P06730 1/20 0.36
▸ MKNK1 Q9BUB5 1/20 0.36
▸ MKNK2 Q9HBH9 1/20 0.36
▸ PDK1 Q15118 1/20 0.36
▸ PDK2 Q15119 1/20 0.36
▸ PDK3 Q15120 1/20 0.36
▸ PDK4 Q16654 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774812 0.89 CYP11B2 (0.42) KDM1AEGLN1SLC22A12EIF4EMKNK1
SCHEMBL30773976 0.89 VNN1 (0.41) KDM1ASTAT3VNN1PTGDR2
SCHEMBL30774866 0.87 POLB (0.47) KDM1AEGLN1SLC22A12EIF4EMKNK1
SCHEMBL30774594 0.86 STAT3 (0.42) KDM1ASTAT3KIF11SLC22A12CETP
SCHEMBL30774573 0.85 CYP11B2 (0.44) EGLN1SLC22A12
SCHEMBL30774365 0.85 STAT3 (0.41) KDM1ASTAT3KIF11SLC22A12VNN1
SCHEMBL30774411 0.84 KDM1A (0.47) KDM1ASTAT3KCNH2KIF11SLC22A12
SCHEMBL31635549 0.84 RIPK1 (0.39) EGLN1SLC22A12
SCHEMBL30774887 0.84 SLC6A9 (0.39) KDM1AKCNH2EGLN1SLC22A12EIF4E
SCHEMBL30774506 0.83 STAT3 (0.44) KDM1ASTAT3EGLN1SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 KDM1A 621/4885STAT3 3957/4885KCNH2 4315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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