SCHEMBL31637547

SCHEMBL31637547

CCOC(=O)[C@@H](C)Oc1ccc2c(-c3ccc(F)cc3N)cc(=O)oc2c1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.57
▸ HPGD P15428 7/20 0.57
▸ KDM4E B2RXH2 6/20 0.51
▸ RECQL P46063 2/20 0.51
▸ ALDH2 P05091 2/20 0.51
▸ HTT P42858 2/20 0.51
▸ LMNA P02545 1/20 0.51
▸ AR P10275 2/20 0.49
▸ HSD17B10 Q99714 2/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ CYP2C9 P11712 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30762863 0.88 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL20839167 0.88 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL30360979 0.88 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL20847991 0.88 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL26115868 0.88 ALDH1A1 (0.64) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL21629565 0.86 ALDH1A1 (0.66) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL21629554 0.83 ALDH1A1 (0.73) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL30762856 0.83 ALDH1A1 (0.62) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL20839368 0.83 ALDH1A1 (0.62) ALDH1A1HPGDKDM4ERECQLALDH2
SCHEMBL30598308 0.82 ALDH1A1 (0.57) ALDH1A1HPGDKDM4ERECQLALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206713-A1 2-[(2-OXO-4-PHENYL-2H-CHROMEN-7-YL)OXY] PROPANAMIDO DERIVATIVES LUNELLA BIOTECH, INC. (CA) 2025-06-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206713-A1 2-[(2-OXO-4-PHENYL-2H-CHROMEN-7-YL)OXY] PROPANAMIDO DERIVATIVES POLRMT, TFAM, POLM ALDH1A1 1696/4885HPGD 3669/4885KDM4E 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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