Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639210 | 0.92 | USP30 (0.38) | NSD2PIK3R1PIK3CAPIK3CDUSP30 | |
| SCHEMBL31639385 | 0.89 | NSD2 (0.38) | TBK1NSD2PIK3CDLRRK2GPR119 | |
| SCHEMBL31639610 | 0.83 | NRAS (0.39) | TBK1LRRK2ALDH1A1EHMT2 | |
| SCHEMBL31000187 | 0.82 | PIK3CA (0.40) | PIK3R1PIK3CALRRK2USP30ALK | |
| SCHEMBL31000188 | 0.82 | PIK3CA (0.40) | PIK3R1PIK3CALRRK2USP30ALK | |
| SCHEMBL30698310 | 0.81 | ALK (0.35) | NSD2PIK3CDGPR119ALKDNMT3A | |
| SCHEMBL30698314 | 0.80 | ALK (0.34) | NSD2PIK3CAPIK3CDLRRK2EHMT2 | |
| SCHEMBL31000192 | 0.79 | CDK4 (0.42) | NSD2ALKDNMT3A | |
| SCHEMBL31639374 | 0.78 | PIK3CD (0.43) | TBK1NSD2PIK3CAPIK3CDLRRK2 | |
| SCHEMBL31739613 | 0.78 | ALK (0.35) | NSD2PIK3CAPIK3CDUSP30EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |