Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639312 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KMT2APOLBCLK1RXFP1 | |
| SCHEMBL31639429 | 0.83 | TGFBR1 (0.35) | EGLN2SRCLRRK2EGFRERBB2 | |
| SCHEMBL31639498 | 0.83 | TGFBR1 (0.35) | EGLN2SRCLRRK2EGFRERBB2 | |
| SCHEMBL31639125 | 0.82 | MTOR (0.40) | PIK3CAMTORGAASMN1; SMN2BCL6 | |
| SCHEMBL31639299 | 0.80 | KHK (0.34) | EGLN2SRCLRRK2EGFRERBB2 | |
| SCHEMBL31000250 | 0.80 | GAA (0.41) | PIK3CAMTORGAASMN1; SMN2BCL6 | |
| SCHEMBL31639610 | 0.79 | NRAS (0.39) | ALDH1A1EGLN2LRRK2 | |
| SCHEMBL31639298 | 0.79 | GABRA1 (0.35) | EGLN2SRCEGFRERBB2 | |
| SCHEMBL31639270 | 0.77 | EGFR (0.33) | EGLN2SRCLRRK2EGFRERBB2 | |
| SCHEMBL15638502 | 0.72 | MAPK1 (0.52) | ALDH1A1KMT2APOLBCLK1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |