Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRAS | P01111 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639195 | 0.92 | FLT3 (0.46) | NRASFLT3LRRK2IRAK4FYN | |
| SCHEMBL31639304 | 0.87 | NRAS (0.39) | NRASFLT3LRRK2IRAK4FYN | |
| SCHEMBL31639307 | 0.83 | TBK1 (0.38) | ALDH1A1TBK1LRRK2EHMT2 | |
| SCHEMBL31639312 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LRRK2EGLN2 | |
| SCHEMBL31639320 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LRRK2EGLN2 | |
| SCHEMBL31000306 | 0.79 | GAA (0.40) | NRASFLT3LRRK2FYN | |
| SCHEMBL27327910 | 0.77 | FLT3 (0.47) | NRASFLT3IRAK4FYN | |
| SCHEMBL27330272 | 0.77 | FLT3 (0.47) | NRASFLT3IRAK4FYN | |
| SCHEMBL30698276 | 0.77 | FLT3 (0.47) | NRASFLT3IRAK4FYN | |
| SCHEMBL27327583 | 0.77 | FLT3 (0.47) | NRASFLT3IRAK4FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |