Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 4/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994244 | 0.87 | PDE3B (0.42) | PDE3BPDE3AMAOAMAOBPRKCI | |
| SCHEMBL19968930 | 0.78 | NPSR1 (0.35) | — | |
| SCHEMBL9165781 | 0.77 | ESR1 (0.51) | PDE3BPDE3AMAOAMAOBESR1 | |
| SCHEMBL9170769 | 0.75 | PDE3B (0.37) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL9168379 | 0.75 | MAOA (0.43) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL9166727 | 0.75 | ESR1 (0.38) | PDE3BPDE3AESR1ESR2 | |
| SCHEMBL15131786 | 0.72 | HSD17B1 (0.34) | — | |
| SCHEMBL562630 | 0.68 | ALDH1A1 (0.33) | PDE3BPDE3AESR1ESR2 | |
| SCHEMBL8994243 | 0.67 | NOS3 (0.49) | PDE3BPDE3ACYP19A1 | |
| SCHEMBL17088272 | 0.67 | HSD17B1 (0.42) | MAOAMAOBPRKCIESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670170-B2 | Resorufin derivatives for treatment of oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2017-06-06 | — | — | US | disclosed |
| EP-0667397-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-0667397-A1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1995-08-16 | — | — | EP | disclosed |
| US-5393615-A | Electrode with acridinone or dibenzoxazepinone mediator on surface | MILES INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0270946-B1 | CHROMOGENIC ACRIDINONE ENZYME SUBSTRATES | MILES INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0459536-A1 | Chromogenic acridinone enzyme substrates | Bayer Corporation (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0459536-A1 | Chromogenic acridinone enzyme substrates | Bayer Corporation (US) | 1991-12-04 | — | — | EP | disclosed |
| US-5045480-A | Gel particles having hapten moieties bound thereto as immunoassay reagent | MILES INC. (US) | 1991-09-03 | — | — | US | disclosed |
| US-4822747-A | STABILIZATION IN AQUEOUS SOLUTION | MILES INC. (US) | 1989-04-18 | — | — | US | disclosed |
| US-4810636-A | HYDROLASES, COLORIMETRIC ANALYSIS | MILES INC. (US) | 1989-03-07 | — | — | US | disclosed |
| US-4810636-A | HYDROLASES, COLORIMETRIC ANALYSIS | MILES INC. (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0270946-A2 | Chromogenic acridinone enzyme substrates | MILES INC. (US) | 1988-06-15 | — | — | EP | disclosed |
| EP-0270946-A2 | Chromogenic acridinone enzyme substrates | MILES INC. (US) | 1988-06-15 | — | — | EP | disclosed |