Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344842 | 0.74 | — | — | |
| SCHEMBL21597311 | 0.74 | — | — | |
| SCHEMBL22765153 | 0.72 | NOS1 (0.36) | ALDH1A1KMT2ALMNA | |
| SCHEMBL4913591 | 0.71 | LMNA (0.33) | LMNA | |
| SCHEMBL4913584 | 0.71 | LMNA (0.33) | LMNA | |
| Nitric Acid SCHEMBL7103201 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28377793 | 0.71 | LMNA (0.39) | KMT2ASMN1; SMN2ATG4BLMNAKDM4E | |
| SCHEMBL14220423 | 0.71 | LMNA (0.39) | KMT2ASMN1; SMN2ATG4BLMNAKDM4E | |
| SCHEMBL625299 | 0.70 | — | — | |
| SCHEMBL8215011 | 0.69 | KMT2A (0.50) | ALDH1A1TSHRKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133468-B1 | METHOD OF PRODUCING N-ALKYL-N'-NITROGUANIDINE | DYNAMIT NOBEL AG (DE) | 2003-08-20 | — | — | EP | claimed |
| EP-0971886-B1 | METHOD FOR PRODUCING N-ALKYL-N'-NITROGUANIDINES | BAYER CROPSCIENCE AG (DE) | 2003-01-15 | — | — | EP | claimed |
| US-6384277-B1 | Method of producing N-alkyl-N′-nitroguanidine | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) | 2002-05-07 | — | — | US | claimed |
| EP-1133468-A1 | METHOD OF PRODUCING N-ALKYL-N'-NITROGUANIDINE | Dynamit Nobel GmbH Explosivstoff- und Systemtechnik (DE) | 2001-09-19 | — | — | EP | claimed |
| US-6114581-A | Method for producing N-alkyl-N'-nitroguanidines | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | claimed |
| WO-2000031025-A1 | METHOD OF PRODUCING N-ALKYL-N'-NITROGUANIDINE | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) | 2000-06-02 | — | — | WO | claimed |
| EP-0971886-A1 | METHOD FOR PRODUCING N-ALKYL-N'-NITROGUANIDINES | BAYER AG (DE) | 2000-01-19 | — | — | EP | claimed |
| WO-1998043951-A1 | METHOD FOR PRODUCING N-ALKYL-N'-NITROGUANIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-08 | — | — | WO | claimed |
| US-7763640-B2 | Substituted oxyguanidines | BAYER CORPSCIENCE AG (DE) | 2010-07-27 | — | — | US | disclosed |
| EP-2184280-A1 | Substituted oxyguanidines | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |
| US-20080312297-A1 | Substituted Oxyguanidines | BAYER CROPSCIENCE AG (DE) | 2008-12-18 | — | — | US | disclosed |
| EP-1819685-A1 | SUBSTITUTED OXYGUANIDINES | Bayer CropScience AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056333-A1 | SUBSTITUTED OXYGUANIDINES | BAYER CROPSCIENCE AG (DE) | 2006-06-01 | — | — | WO | disclosed |
| CN-1207279-C | Process for preparing N-alkyl-N' -nitroguanidines | DYNAMIT NOBEL EXPLOSIVSTOFF UN (DE) | 2005-06-22 | — | — | CN | disclosed |
| CN-1251089-A | Method for producing N-alkyl-N'-nitroguanidines | BAYER AG (DE) | 2000-04-19 | — | — | CN | disclosed |
| CN-1251089-A | Method for producing N-alkyl-N'-nitroguanidines | BAYER AG (DE) | 2000-04-19 | — | — | CN | disclosed |
| EP-0971886-A1 | METHOD FOR PRODUCING N-ALKYL-N'-NITROGUANIDINES | BAYER AG (DE) | 2000-01-19 | — | — | EP | disclosed |
| EP-0971886-A1 | METHOD FOR PRODUCING N-ALKYL-N'-NITROGUANIDINES | BAYER AG (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998043951-A1 | METHOD FOR PRODUCING N-ALKYL-N'-NITROGUANIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-08 | — | — | WO | disclosed |
| WO-1998043951-A1 | METHOD FOR PRODUCING N-ALKYL-N'-NITROGUANIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312297-A1 | Substituted Oxyguanidines | OGA, CAT, OGG1 | ALDH1A1 1777/4885TSHR 1627/4885KMT2A 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.