Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164502 | 0.81 | HTT (0.36) | PARP1LMNAALDH1A1TP53HTT | |
| SCHEMBL9792276 | 0.78 | ALDH1A1 (0.50) | LMNAALDH1A1HTTALOX15CES2 | |
| SCHEMBL9792285 | 0.76 | KMT2A (0.48) | ALDH1A1HTTALOX15HPGDCES2 | |
| SCHEMBL1168105 | 0.73 | HTT (0.43) | PARP1LMNAALDH1A1HTTALOX15 | |
| SCHEMBL3174176 | 0.72 | CYP2D6 (0.45) | HTTALOX15RAB9AMEN1NPC1 | |
| SCHEMBL6133148 | 0.72 | ALDH1A1 (0.40) | ALDH1A1HTTRAB9AMEN1NPC1 | |
| SCHEMBL10848882 | 0.70 | — | — | |
| SCHEMBL428172 | 0.69 | — | — | |
| SCHEMBL27967553 | 0.68 | PLG (0.37) | HTTMEN1KMT2A | |
| SCHEMBL8305175 | 0.68 | LMNA (0.70) | LMNAALDH1A1HTTALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718277-B2 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718087-B2 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7704610-B2 | organic light emitting device comprising deuterated organic iridium complex; optoelectronic devices, photovoltaic devices; enhanced color properties and light output efficiencies | GENERAL ELECTRIC COMPANY (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100090586-A1 | ELECTRONIC DEVICES COMPRISING ORGANIC IRIDIUM COMPOSITIONS | GENERAL ELECTRIC COMPANY | 2010-04-15 | — | — | US | disclosed |
| US-7695640-B2 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY (US) | 2010-04-13 | — | — | US | disclosed |
| US-7691292-B2 | organic light emitters; photovoltaic cells; electrophosphorescent | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-7691494-B2 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-20100051869-A1 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY | 2010-03-04 | — | — | US | disclosed |
| US-7652151-B2 | Ketopyrroles useful as ligands in organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-01-26 | — | — | US | disclosed |
| US-7608677-B2 | Method for preparing polymeric organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| EP-2049555-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2009-04-22 | — | — | EP | disclosed |
| US-20080023672-A1 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026249-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080023671-A1 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026250-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080027028-A1 | Ketopyrroles useful as ligands in organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| WO-2008014037-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | WO | disclosed |
| US-20080026477-A1 | Method for preparing polymeric organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027028-A1 | Ketopyrroles useful as ligands in organic iridium compositions | OR10J3, OPRD1, OCIAD1 | PARP1 1003/4885LMNA 4454/4885ALDH1A1 2880/4885 |
| US-20100051869-A1 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | OCIAD1, OCIAD2, OXER1 | PARP1 2155/4885LMNA 4875/4885ALDH1A1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.