Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649185 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31649296 | 0.92 | HTR2A (0.40) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31649151 | 0.89 | ACHE (0.43) | — | |
| SCHEMBL31649223 | 0.89 | SLC6A2 (0.40) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31649462 | 0.89 | ACHE (0.43) | — | |
| SCHEMBL31649412 | 0.86 | KMT2A (0.43) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31649370 | 0.86 | KMT2A (0.43) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31649053 | 0.85 | KMT2A (0.40) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31649406 | 0.85 | KMT2A (0.40) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31649325 | 0.84 | KMT2A (0.40) | ALDH1A1KDM4EMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | claimed |
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |