Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 2/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649151 | 1.00 | ACHE (0.43) | ACHEOPRM1CCR5CHRM5HTT | |
| SCHEMBL31649409 | 0.91 | RORC (0.40) | ACHEHSD11B1LTA4H | |
| SCHEMBL31649221 | 0.90 | HSD11B1 (0.40) | UBE2MDCUN1D1HSD11B1 | |
| SCHEMBL31649158 | 0.89 | ALDH1A1 (0.46) | — | |
| SCHEMBL31649185 | 0.89 | ALDH1A1 (0.46) | — | |
| SCHEMBL31649296 | 0.89 | HTR2A (0.40) | CCR5KCNA5HSD11B1SIGMAR1 | |
| SCHEMBL31649339 | 0.86 | DPP4 (0.42) | OPRM1DPP4FAPDPP8DPP9 | |
| SCHEMBL31649065 | 0.85 | TACR1 (0.39) | DPP4FAPDPP8DPP9HSD11B1 | |
| SCHEMBL31649089 | 0.84 | DPP4 (0.41) | OPRM1UBE2MDCUN1D1DPP4FAP | |
| SCHEMBL31649309 | 0.82 | ACHE (0.43) | ACHEOPRM1CCR5HTTCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |