Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 7/20 | 0.40 |
| ▸ | CTRC | Q99895 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649439 | 0.94 | HTR1A (0.44) | ACEF2PRSS1CMA1CTRC | |
| SCHEMBL31649265 | 0.91 | ACE (0.45) | ACEF2PRSS1CMA1NPC1 | |
| Hydrochloric Acid SCHEMBL31649337 | 0.89 | F2 (0.41) | ACEF2PRSS1CMA1CTRC | |
| SCHEMBL31649181 | 0.85 | ACE (0.47) | ACEMMP9MMP1MMP3NPC1 | |
| SCHEMBL31649445 | 0.81 | ACE (0.46) | ACENPC1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL31649424 | 0.80 | ACE (0.46) | ACENPC1RAB9ASMN1; SMN2HTR1A | |
| SCHEMBL31649231 | 0.79 | ACE (0.45) | ACEF2PRSS1CMA1CTRC | |
| SCHEMBL31649054 | 0.78 | AKT1 (0.49) | ACEMMP9MMP1MMP3SCN9A | |
| SCHEMBL28538006 | 0.78 | AKT1 (0.49) | ACEMMP9MMP1MMP3SCN9A | |
| SCHEMBL31649183 | 0.77 | DPP7 (0.51) | NPC1RAB9ASMN1; SMN2HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |