Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 9/20 | 0.40 |
| ▸ | CTRC | Q99895 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649055 | 0.91 | ACE (0.46) | ACEF2PRSS1NPC1RAB9A | |
| SCHEMBL31649422 | 0.83 | DPP7 (0.45) | ACEF2PRSS1NPC1RAB9A | |
| SCHEMBL31649212 | 0.80 | ACE (0.47) | ACENPC1RAB9ASMN1; SMN2ITGB3 | |
| SCHEMBL31649340 | 0.79 | TACR1 (0.41) | KMT2AMAPK1 | |
| SCHEMBL31228403 | 0.79 | PPARA (0.49) | ACEITGB3ITGA2B | |
| SCHEMBL31306238 | 0.79 | PPARA (0.49) | ACEITGB3ITGA2B | |
| SCHEMBL31649159 | 0.79 | ACE (0.44) | ACEF2PRSS1NPC1RAB9A | |
| SCHEMBL31649025 | 0.78 | DPP7 (0.41) | F2PRSS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31526993 | 0.77 | KLK5 (0.46) | ACEKLK5 | |
| SCHEMBL31649265 | 0.76 | ACE (0.45) | ACEF2PRSS1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |