Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 6/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649159 | 0.91 | ACE (0.44) | ACEKLK5F2PRSS1NPC1 | |
| SCHEMBL31649439 | 0.88 | HTR1A (0.44) | ACEF2PRSS1MAPK1CMA1 | |
| Hydrochloric Acid SCHEMBL31649337 | 0.84 | F2 (0.41) | ACEF2PRSS1CMA1 | |
| SCHEMBL31649391 | 0.78 | ACE (0.50) | ACEKLK5F2PRSS1KMT2A | |
| SCHEMBL31649055 | 0.78 | ACE (0.46) | ACEKLK5F2PRSS1KMT2A | |
| SCHEMBL31649285 | 0.77 | PPARA (0.51) | ACE | |
| SCHEMBL6388649 | 0.77 | AKT1 (0.46) | ACE | |
| SCHEMBL31649348 | 0.77 | CTSS (0.47) | ACE | |
| SCHEMBL31649231 | 0.76 | ACE (0.45) | ACEKLK5F2PRSS1KMT2A | |
| SCHEMBL31649045 | 0.76 | DPP7 (0.47) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |