Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649424 | 0.97 | ACE (0.46) | ACEACE2HTR1AHTR7HRH1 | |
| SCHEMBL31649181 | 0.96 | ACE (0.47) | ACEACE2HTR1AHTR7HRH1 | |
| SCHEMBL31649439 | 0.84 | HTR1A (0.44) | ACEHTR1AHTR7HRH1DRD3 | |
| Hydrochloric Acid SCHEMBL31649337 | 0.81 | F2 (0.41) | ACEHTR1AHTR7HRH1DRD3 | |
| SCHEMBL31649159 | 0.81 | ACE (0.44) | ACEHTR1AHTR7HRH1DRD3 | |
| SCHEMBL31649210 | 0.80 | ACE (0.47) | ACEACE2HRH1DPP4DPP8 | |
| SCHEMBL31649228 | 0.76 | ACE (0.45) | ACEACE2DPP4ALDH1A1PREP | |
| Hydrochloric Acid SCHEMBL31649315 | 0.76 | DPP4 (0.52) | HTR1AHTR7HRH1DRD3HTR2B | |
| SCHEMBL31649265 | 0.75 | ACE (0.45) | ACEELANEMAPK1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL31649106 | 0.73 | HTR1A (0.52) | HTR1AHTR7HRH1DRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |