Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649055 | 0.87 | ACE (0.46) | ACEELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649231 | 0.80 | ACE (0.45) | ACEELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649025 | 0.79 | DPP7 (0.41) | NPC1RAB9ASMN1; SMN2DPP4DPP8 | |
| SCHEMBL3822519 | 0.79 | SMN1; SMN2 (0.42) | ACEACE2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649210 | 0.79 | ACE (0.47) | ACEACE2ELANENPC1RAB9A | |
| SCHEMBL31649181 | 0.76 | ACE (0.47) | ACEACE2ELANENPC1RAB9A | |
| SCHEMBL31649328 | 0.76 | TACR1 (0.42) | DPP7ALDH1A1 | |
| SCHEMBL31649422 | 0.76 | DPP7 (0.45) | ACENPC1RAB9ASMN1; SMN2DPP4 | |
| SCHEMBL31649445 | 0.76 | ACE (0.46) | ACEACE2ELANENPC1RAB9A | |
| SCHEMBL31649228 | 0.76 | ACE (0.45) | ACEACE2ELANENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |