Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649210 | 0.87 | ACE (0.47) | ACEACE2ITGB3ITGA2BELANE | |
| SCHEMBL31649348 | 0.82 | CTSS (0.47) | ACEITGB3ITGA2BCTSKCTSL | |
| SCHEMBL31649181 | 0.77 | ACE (0.47) | ACEACE2PREPELANEDPP4 | |
| SCHEMBL31649445 | 0.76 | ACE (0.46) | ACEACE2PREPELANEDPP4 | |
| SCHEMBL31649212 | 0.76 | ACE (0.47) | ACEACE2PREPITGB3ITGA2B | |
| SCHEMBL31649424 | 0.76 | ACE (0.46) | ACEACE2PREPELANEDPP4 | |
| SCHEMBL8569656 | 0.72 | CTSS (0.43) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8561162 | 0.72 | CTSS (0.41) | NPC1RAB9ASMN1; SMN2CTSKCTSL | |
| SCHEMBL31649201 | 0.70 | DPP7 (0.55) | DPP4 | |
| SCHEMBL9705353 | 0.69 | ACE (0.61) | ACEACE2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |