Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.46 |
| ▸ | DPP4 | P27487 | 8/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.39 |
| ▸ | FAP | Q12884 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649426 | 0.81 | DPP7 (0.42) | DPP7DPP4ACE | |
| SCHEMBL31649064 | 0.80 | DPP7 (0.42) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL31649357 | 0.79 | DPP7 (0.40) | DPP7DPP4ACE | |
| SCHEMBL801893 | 0.77 | EPHX1 (0.46) | DPP4EPHX1L3MBTL1NPC1RAB9A | |
| SCHEMBL9963473 | 0.76 | CTSK (0.40) | DPP7EPHX1L3MBTL1TDP1 | |
| SCHEMBL31649419 | 0.75 | SYK (0.54) | DPP4DPP8ACE | |
| SCHEMBL6792077 | 0.75 | CTSK (0.40) | DPP7DPP8EPHX1L3MBTL1 | |
| SCHEMBL31649348 | 0.74 | CTSS (0.47) | ACE | |
| SCHEMBL31649050 | 0.74 | DPP7 (0.60) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL27004682 | 0.74 | EPHX1 (0.43) | EPHX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |