Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.47 |
| ▸ | CTSK | P43235 | 13/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649228 | 0.82 | ACE (0.45) | CTSSCTSKACECTSLITGB3 | |
| SCHEMBL31649426 | 0.81 | DPP7 (0.42) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL31649357 | 0.79 | DPP7 (0.40) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL31649265 | 0.77 | ACE (0.45) | ACE | |
| SCHEMBL31649055 | 0.76 | ACE (0.46) | ACECTSL | |
| SCHEMBL31649159 | 0.76 | ACE (0.44) | ACEITGB3ITGA2B | |
| SCHEMBL31649391 | 0.76 | ACE (0.50) | ACECTSL | |
| SCHEMBL31649231 | 0.74 | ACE (0.45) | ACEITGB3ITGA2B | |
| SCHEMBL31649255 | 0.74 | DPP7 (0.46) | ACE | |
| SCHEMBL8250574 | 0.73 | DPP4 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |