Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15222152 | 0.88 | CD44 (0.47) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL15268227 | 0.88 | KDM4E (0.36) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL19055863 | 0.86 | KDM1A (0.46) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL15222147 | 0.80 | DRD1 (0.38) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL15222154 | 0.78 | CD44 (0.37) | CD44CYP3A4TDP1 | |
| SCHEMBL29471735 | 0.74 | BCL2L1 (0.43) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL16671956 | 0.74 | TDP2 (0.36) | MEN1KMT2AKDM1AMAOBCYP2C9 | |
| SCHEMBL3835567 | 0.74 | BCL2L1 (0.43) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL20445641 | 0.74 | ALDH1A1 (0.39) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL20445650 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250229262-A1 | CHIRAL SPIROCYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF | SPHENOTECH CO., LIMITED (CN) | 2025-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250229262-A1 | CHIRAL SPIROCYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF | PKD1, PKD2, SYMPK | ALDH1A1 2502/4885HPGD 1037/4885MEN1 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.