Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471735 | 1.00 | BCL2L1 (0.43) | BCL2L1BADHTR1AHTR1BHTR2A | |
| SCHEMBL23023370 | 0.78 | BCL2L1 (0.41) | BCL2L1BADHTR1AHTR1BHTR2A | |
| SCHEMBL13999140 | 0.77 | BCL2L1 (0.31) | BCL2L1BADHTR1AHTR1BHTR2A | |
| SCHEMBL28739309 | 0.77 | MAP2K1 (0.40) | BCL2L1BADHTR1AHTR1BHTR2A | |
| SCHEMBL31661007 | 0.74 | ALDH1A1 (0.43) | HTR1AHTR1BHTR2AHTR2CHTR7 | |
| SCHEMBL34466342 | 0.74 | MEN1 (0.40) | BCL2L1BADHTR1AHTR1BHTR2A | |
| SCHEMBL21726270 | 0.74 | — | — | |
| SCHEMBL13899940 | 0.72 | HTR1A (0.38) | BCL2L1BADHTR1AHTR1BHTR2A | |
| SCHEMBL24712825 | 0.72 | CHRNE (0.34) | HTR1AHTR1BHTR2AHTR2CHTR7 | |
| SCHEMBL19010372 | 0.71 | TRPA1 (0.39) | BCL2L1BADHTR1AHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2025-01-14 | — | — | US | claimed |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | GUANGDONG OXO CHEM LTD. (CN) | 2022-08-04 | — | — | US | claimed |
| CN-108658774-B | Synthesis method of novel chiral nitrobinaphthol and derivatives thereof | 中国科学院青岛生物能源与过程研究所 | 2020-11-27 | — | — | CN | claimed |
| US-12637403-B2 | Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2026-05-26 | — | — | US | disclosed |
| US-12291497-B2 | 3,3,3′,3′-tetramethyl-1,1′-spirobiindane-7,7′-diol | ZHEJIANG UNIVERSITY (CN) | 2025-05-06 | — | — | US | disclosed |
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2025-01-14 | — | — | US | disclosed |
| CN-118652278-A | Chiral silicon spiro phosphine-oxazoline ligand, ionic iridium complex, preparation method and application thereof | 复旦大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-118515601-A | Preparation method of anti-tumor isoindolinone compound | 华东理工大学 | 2024-08-20 | — | — | CN | disclosed |
| US-20240166586-A1 | ACCESS TO CHIRAL BISPHENOL (BPOL) LIGANDS THROUGH DESYMMETRIZING ASYMMETRIC ORTHO-SELECTIVE MONO-HALOGENATION | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-05-23 | — | — | US | disclosed |
| US-20240066509-A1 | CHIRAL PHOSPHORIC ACIDS IMMOBILIZED ON SOLID SUPPORT FOR THE SELECTIVE PROTECTION OF HYDROXYL GROUPS | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-02-29 | — | — | US | disclosed |
| US-11905237-B2 | Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-02-20 | — | — | US | disclosed |
| EP-1957611-A1 | TEMPERATURE COMPENSATING CHIRAL DOPANTS | Industrial Technology Research Institute (TW) | 2008-08-20 | — | — | EP | disclosed |
| US-7329368-B2 | Temperature compensating chiral dopants | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-02-12 | — | — | US | disclosed |
| US-20070131901-A1 | Temperature compensating chiral dopants | EASTMAN KODAK COMPANY | 2007-06-14 | — | — | US | disclosed |
| WO-2007067481-A1 | TEMPERATURE COMPENSATING CHIRAL DOPANTS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2007-06-14 | — | — | WO | disclosed |
| EP-1663927-A2 | CHIRAL COMPOUNDS AND COMPOSITIONS CONTAINING THE SAME | EASTMAN KODAK COMPANY (US) | 2006-06-07 | — | — | EP | disclosed |
| US-7052743-B2 | Chiral compounds and compositions containing the same | EASTMAN KODAK COMPANY (US) | 2006-05-30 | — | — | US | disclosed |
| US-20060091357-A1 | Photochemically active chiral compounds and compositions containing the same | IRIS OPTRONICS CO., LTD. (TW) | 2006-05-04 | — | — | US | disclosed |
| US-20050072961-A1 | Chiral compounds and compositions containing the same | EASTMAN KODAK COMPANY | 2005-04-07 | — | — | US | disclosed |
| WO-2005023742-A2 | CHIRAL COMPOUNDS AND COMPOSITIONS CONTAINING THE SAME | EASTMAN KODAK COMPANY (US) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066509-A1 | CHIRAL PHOSPHORIC ACIDS IMMOBILIZED ON SOLID SUPPORT FOR THE SELECTIVE PROTECTION OF HYDROXYL GROUPS | PYGL, PSPH, HAO2 | BCL2L1 4580/4885BAD 2652/4885HTR1A 3731/4885 |
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | SOST, BPGM, PFKFB3 | BCL2L1 1378/4885BAD 706/4885HTR1A 4196/4885 |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | SOST, BPGM, PFKFB3 | BCL2L1 1378/4885BAD 706/4885HTR1A 4196/4885 |
| US-20070131901-A1 | Temperature compensating chiral dopants | IDO2, IDO1, CRY2 | BCL2L1 2408/4885BAD 4577/4885HTR1A 516/4885 |
| US-12637403-B2 | Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation | NR4A1, BRPF3, BPTF | BCL2L1 948/4885BAD 1494/4885HTR1A 2370/4885 |
| US-20060091357-A1 | Photochemically active chiral compounds and compositions containing the same | GNG2, CRY2, CRY1 | BCL2L1 757/4885BAD 4140/4885HTR1A 2918/4885 |
| US-12291497-B2 | 3,3,3′,3′-tetramethyl-1,1′-spirobiindane-7,7′-diol | BPGM, PHOSPHO1, TALDO1 | BCL2L1 3832/4885BAD 2835/4885HTR1A 1438/4885 |
| US-20240166586-A1 | ACCESS TO CHIRAL BISPHENOL (BPOL) LIGANDS THROUGH DESYMMETRIZING ASYMMETRIC ORTHO-SELECTIVE MONO-HALOGENATION | OSBP, BICRA, BRPF3 | BCL2L1 1106/4885BAD 875/4885HTR1A 3532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.