Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | FBP1 | P09467 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FHIT | P49789 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661345 | 0.87 | FBP1 (0.72) | ALDH1A1CYP1A2FBP1HPGDLMNA | |
| SCHEMBL535765 | 0.85 | L3MBTL1 (0.56) | ALDH1A1CYP1A2FBP1HPGDMAPT | |
| SCHEMBL28733822 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP1A2FBP1HPGDLMNA | |
| SCHEMBL4135529 | 0.83 | FBP1 (0.80) | ALDH1A1CYP1A2FBP1HPGDLMNA | |
| SCHEMBL31661267 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP1A2FBP1HPGDLMNA | |
| SCHEMBL289441 | 0.83 | ALDH1A1 (0.73) | ALDH1A1CYP1A2FBP1HPGDLMNA | |
| SCHEMBL29235553 | 0.82 | FBP1 (0.59) | ALDH1A1CYP1A2FBP1HPGDLMNA | |
| SCHEMBL594323 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP1A2FBP1HPGDLMNA | |
| Bromide SCHEMBL16637333 | 0.81 | ALDH1A1 (0.71) | ALDH1A1CYP1A2FBP1HPGDLMNA | |
| SCHEMBL4971356 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151402-A1 | THIAZOLE TRPML1 AGONISTS AND USES THEREOF | LIBRA THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |