Sugi Predict

Sugi Predict / Compounds / SCHEMBL289441

SCHEMBL289441

SCHEMBL289441

CCOC(=O)c1nc(N)sc1C

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.73
▸ CYP1A2 P05177 1/20 0.73
▸ GAA P10253 4/20 0.55
▸ HPGD P15428 4/20 0.54
▸ MAPT P10636 5/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ FHIT P49789 1/20 0.50
▸ KMT2A Q03164 4/20 0.49
▸ MEN1 O00255 3/20 0.49
▸ HSD17B10 Q99714 2/20 0.49
▸ RAB9A P51151 4/20 0.49
▸ NPC1 O15118 3/20 0.49
▸ FBP1 P09467 1/20 0.48
▸ LMNA P02545 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL16637333 0.98 ALDH1A1 (0.71) ALDH1A1CYP1A2GAAHPGDMAPT
SCHEMBL3119761 0.84 ALDH1A1 (1.00) ALDH1A1CYP1A2GAAHPGDMAPT
SCHEMBL595150 0.83 ALDH1A1 (0.69) ALDH1A1CYP1A2GAAHPGDMAPT
SCHEMBL3056715 0.83 ALDH1A1 (0.69) ALDH1A1CYP1A2GAAHPGDMAPT
SCHEMBL960280 0.83 ALDH1A1 (0.69) ALDH1A1CYP1A2GAAHPGDMAPT
SCHEMBL12228834 0.83 ALDH1A1 (0.69) ALDH1A1CYP1A2GAAHPGDMAPT
SCHEMBL31661235 0.83 ALDH1A1 (0.69) ALDH1A1CYP1A2GAAHPGDMAPT
SCHEMBL4146195 0.82 FBP1 (0.67) ALDH1A1CYP1A2GAAHPGDKMT2A
SCHEMBL2616832 0.81 GAA (0.58) ALDH1A1CYP1A2GAAHPGDMAPT
SCHEMBL794531 0.81 ALDH1A1 (0.55) ALDH1A1CYP1A2GAAHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3717465-B1 COMPOUNDS STEP PHARMA S A S (FR) 2026-01-21 — — EP disclosed
US-20250263407-A1 Compounds STEP PHARMA S.A.S. (FR) 2025-08-21 — — US disclosed
US-12319680-B2 Compounds STEP PHARMA S.A.S. (FR) 2025-06-03 — — US disclosed
CN-114630822-B Biaryl dihydroorotate acid dehydrogenase inhibitors 詹森生物科技公司 2024-10-01 — — CN disclosed
US-20240158414-A1 BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS JANSSEN BIOTECH, INC. 2024-05-16 — — US disclosed
EP-4041714-B1 BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS JANSSEN BIOTECH INC (US) 2023-12-13 — — EP disclosed
US-20230331767-A1 TARGETED STEROID COMPOUNDS PURDUE RESEARCH FOUNDATION 2023-10-19 — — US disclosed
US-20230183229-A1 Compounds SYGNATURE DISCOVERY LIMITED (GB) 2023-06-15 — — US disclosed
US-11505547-B2 Compounds STEP PHARMA S.A.S. (FR) 2022-11-22 — — US disclosed
EP-4041714-A1 BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS Janssen Biotech, Inc. (US) 2022-08-17 — — EP disclosed
US-20080139558-A1 QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS KALYPSYS, INC. (US) 2008-06-12 — — US disclosed
WO-2008063867-A2 TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2008-05-29 — — WO disclosed
EP-1853586-A1 ANTIBACTERIAL PIPERIDINE DERIVATIVES AstraZeneca AB (SE) 2007-11-14 — — EP disclosed
WO-2007117778-A2 QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS KALYPSYS, INC. (US) 2007-10-18 — — WO disclosed
WO-2006087543-A1 ANTIBACTERIAL PIPERIDINE DERIVATIVES ASTRAZENECA AB (SE) 2006-08-24 — — WO disclosed
EP-0700394-B1 HERBICIDAL THIAZOLE DERIVATIVES SHELL INT RESEARCH (NL) 1998-04-01 — — EP disclosed
US-5693594-A Herbicidal thiazole derivatives AMERICAN CYANAMID COMPANY (US) 1997-12-02 — — US disclosed
EP-0700394-A1 HERBICIDAL THIAZOLE DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1996-03-13 — — EP disclosed
WO-1994027983-A1 HERBICIDAL THIAZOLE DERIVATIVES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1994-12-08 — — WO disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331767-A1 TARGETED STEROID COMPOUNDS CYP11B2, FOLR2, CYP11B1 ALDH1A1 1388/4885CYP1A2 109/4885GAA 3035/4885
US-20230183229-A1 Compounds UGT1A1, CYP1A1, CYP1B1 ALDH1A1 158/4885CYP1A2 7/4885GAA 546/4885
US-12319680-B2 Compounds UGT1A1, CYP1A1, CYP1B1 ALDH1A1 158/4885CYP1A2 7/4885GAA 546/4885
US-20250263407-A1 Compounds CYP1A1, UGT1A1, CYP1A2 ALDH1A1 166/4885CYP1A2 3/4885GAA 595/4885
US-20080139558-A1 QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS NOS2, NOS1, NQO2 ALDH1A1 1044/4885CYP1A2 54/4885GAA 542/4885
US-11505547-B2 Compounds UGT1A1, CYP1A1, CYP1B1 ALDH1A1 158/4885CYP1A2 7/4885GAA 546/4885
US-20240158414-A1 BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS DHODH, DLD, DPYD ALDH1A1 54/4885CYP1A2 259/4885GAA 263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.