Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661270 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL31661267 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP1A2HDAC4HDAC6HDAC3 | |
| SCHEMBL3117271 | 0.81 | ALDH1A1 (0.45) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL31661321 | 0.81 | FBP1 (0.50) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL18039311 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP1A2HDAC4HDAC6HDAC3 | |
| SCHEMBL9861374 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL2826874 | 0.77 | GAA (0.55) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL1505552 | 0.75 | ALDH1A1 (0.66) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL26984582 | 0.74 | TARBP2 (0.42) | ALDH1A1CYP1A2HDAC4HDAC6HDAC3 | |
| SCHEMBL18039308 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TARBP2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151402-A1 | THIAZOLE TRPML1 AGONISTS AND USES THEREOF | LIBRA THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |