Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 10/20 | 0.64 |
| ▸ | NNMT | P40261 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865853 | 1.00 | HCAR3 (0.64) | HCAR3NNMTGSK3BPTPN1HCAR2 | |
| Bromide SCHEMBL16753536 | 0.98 | HCAR3 (0.62) | HCAR3NNMTGSK3BPTPN1HCAR2 | |
| SCHEMBL31661260 | 0.83 | HCAR3 (0.69) | HCAR3NNMTGSK3BPTPN1HCAR2 | |
| SCHEMBL1203341 | 0.83 | PTK2 (0.54) | HCAR3NNMTGSK3BPTPN1 | |
| SCHEMBL24285432 | 0.83 | HCAR3 (0.64) | HCAR3NNMTHCAR2 | |
| SCHEMBL6074331 | 0.81 | HDAC3 (0.47) | HCAR3NNMTGSK3BPTPN1HCAR2 | |
| SCHEMBL30320778 | 0.81 | GSK3B (0.46) | HCAR3NNMTGSK3BPTPN1 | |
| SCHEMBL25702957 | 0.81 | GSK3B (0.46) | HCAR3NNMTGSK3BPTPN1 | |
| SCHEMBL9772954 | 0.80 | ALDH1A1 (0.51) | HCAR3GSK3BHCAR2 | |
| SCHEMBL10084182 | 0.79 | HCAR3 (0.41) | HCAR3NNMTGSK3BPTPN1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |