Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.38 |
| ▸ | METAP2 | P50579 | 6/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661400 | 0.92 | PARP1 (0.38) | METAP2PIK3CAAURKARPS6KB1NR1H2 | |
| SCHEMBL31661358 | 0.87 | IDO1 (0.38) | PTGER4METAP2PIK3CAAURKARPS6KB1 | |
| SCHEMBL31661401 | 0.83 | METAP2 (0.35) | PTGER4METAP2PIK3CA | |
| SCHEMBL31661377 | 0.82 | METAP2 (0.38) | PTGER4METAP2PIK3CANR1H2 | |
| SCHEMBL31661333 | 0.78 | PTGER4 (0.38) | PTGER4METAP2 | |
| SCHEMBL31661382 | 0.77 | TSHR (0.40) | PTGER4METAP2 | |
| SCHEMBL30961843 | 0.72 | PTGER4 (0.42) | PTGER4METAP2PIK3CA | |
| SCHEMBL3883176 | 0.71 | KDM4E (0.45) | NNMT | |
| SCHEMBL30961819 | 0.71 | PTGER4 (0.41) | PTGER4METAP2 | |
| SCHEMBL31661369 | 0.71 | PTGER4 (0.37) | PTGER4METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |