Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661401 | 0.92 | METAP2 (0.35) | METAP2MAPTIRAK4PIK3CAALDH1A1 | |
| SCHEMBL31661400 | 0.91 | PARP1 (0.38) | METAP2NR1H2PIK3CA | |
| SCHEMBL31661382 | 0.86 | TSHR (0.40) | METAP2L3MBTL1MAPK1HSD17B10PTGER4 | |
| SCHEMBL31661335 | 0.82 | PTGER4 (0.38) | METAP2NR1H2PIK3CAPTGER4 | |
| SCHEMBL31661333 | 0.77 | PTGER4 (0.38) | METAP2EGFRL3MBTL1HSD17B10PTGER4 | |
| SCHEMBL30961772 | 0.76 | KDM4E (0.33) | METAP2ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL31661358 | 0.76 | IDO1 (0.38) | METAP2PIK3CAEGFRPTGER4 | |
| SCHEMBL30961779 | 0.71 | PTGER4 (0.31) | PTGER4 | |
| SCHEMBL30961782 | 0.71 | METAP2 (0.32) | METAP2PTGER4 | |
| SCHEMBL30961784 | 0.67 | MAPT (0.32) | METAP2MAPTL3MBTL1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |