Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30538321 | 0.83 | MAPT (0.52) | CYP3A4MAPTKDM4ELMNANR4A2 | |
| SCHEMBL27085550 | 0.80 | CYP3A4 (0.49) | CYP3A4MAPTKDM4ELMNANR4A2 | |
| SCHEMBL7846153 | 0.79 | CYP3A4 (0.47) | CYP3A4MAPTKDM4ELMNANR4A2 | |
| SCHEMBL10978833 | 0.76 | CYP19A1 (0.58) | CYP3A4MAPTKDM4ELMNAKMT2A | |
| SCHEMBL11219318 | 0.75 | HSD17B10 (0.63) | CYP3A4MAPTKDM4ELMNAMEN1 | |
| SCHEMBL28718999 | 0.75 | MAPT (0.50) | CYP3A4MAPTKDM4ELMNAMEN1 | |
| SCHEMBL4464552 | 0.75 | MAPT (0.50) | CYP3A4MAPTKDM4ELMNAMEN1 | |
| SCHEMBL29275406 | 0.74 | ALDH1A1 (0.53) | CYP3A4MAPTKDM4ELMNAMEN1 | |
| SCHEMBL30494604 | 0.74 | ALDH1A1 (0.53) | CYP3A4MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7354479 | 0.73 | CYP3A4 (0.41) | CYP3A4MAPTKDM4ELMNANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |