SCHEMBL30494604

SCHEMBL30494604

Clc1cc2ccc3ccccc3c2[nH]1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
HSD17B10 Q99714 4/20 0.53
HPGD P15428 2/20 0.53
MEN1 O00255 1/20 0.53
USP2 O75604 1/20 0.53
KMT2A Q03164 1/20 0.53
KIF11 P52732 1/20 0.47
KDM4E B2RXH2 3/20 0.44
RAB9A P51151 2/20 0.44
SIRT2 Q8IXJ6 1/20 0.44
SIRT1 Q96EB6 1/20 0.44
CYP2A6 P11509 4/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPC1 O15118 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
MCL1 Q07820 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29275406 1.00 ALDH1A1 (0.53) ALDH1A1HSD17B10HPGDMEN1USP2
SCHEMBL28669933 0.77 ALDH1A1 (0.55) ALDH1A1HSD17B10HPGDMEN1USP2
SCHEMBL3433646 0.75 ALDH1A1 (0.53) ALDH1A1HSD17B10HPGDMEN1USP2
SCHEMBL4916031 0.75 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDMEN1USP2
SCHEMBL7915531 0.75 ALDH1A1 (0.66) ALDH1A1HSD17B10HPGDMEN1USP2
SCHEMBL31661367 0.74 CYP3A4 (0.49) ALDH1A1MEN1KMT2AKDM4ERAB9A
SCHEMBL28311954 0.74 DAO (0.56) KDM4ECYP2A6CYP1A2
Iodide SCHEMBL27218977 0.73 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDMEN1USP2
SCHEMBL6648718 0.73 MEN1 (0.49) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL31020778 0.72 RAB9A (0.55) ALDH1A1HSD17B10HPGDMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116438946-A Organic light emitting device 株式会社LG化学 2023-07-14 CN disclosed