Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661543 | 0.94 | S1PR1 (0.45) | THRBKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL31661668 | 0.88 | SMN1; SMN2 (0.49) | THRBHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL31661774 | 0.88 | TP53 (0.51) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL31661582 | 0.87 | USP1 (0.46) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL31661691 | 0.87 | S1PR1 (0.38) | THRBKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31661537 | 0.86 | NPC1 (0.41) | THRBKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31661641 | 0.86 | S1PR1 (0.46) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL31661573 | 0.85 | PTGS1 (0.41) | THRBMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31661770 | 0.85 | S1PR1 (0.43) | THRBKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL31661680 | 0.84 | NPC1 (0.38) | THRBMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |