Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP1 | O94782 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661692 | 0.90 | RAB9A (0.39) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 | |
| SCHEMBL31661606 | 0.90 | RAB9A (0.44) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 | |
| SCHEMBL31661749 | 0.89 | RAB9A (0.38) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 | |
| SCHEMBL31661565 | 0.88 | THRB (0.47) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 | |
| SCHEMBL31661543 | 0.87 | S1PR1 (0.45) | SMN1; SMN2MEN1KMT2AS1PR1HSD17B10 | |
| SCHEMBL31661774 | 0.86 | TP53 (0.51) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 | |
| SCHEMBL31661618 | 0.85 | HSD11B1 (0.47) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 | |
| SCHEMBL31661698 | 0.85 | USP1 (0.38) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 | |
| SCHEMBL31661582 | 0.84 | USP1 (0.46) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 | |
| SCHEMBL31661788 | 0.83 | USP1 (0.42) | SMN1; SMN2HPGDMEN1KMT2AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |