Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.52 |
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.52 |
| ▸ | RELA | Q04206 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661551 | 0.91 | NPC1 (0.44) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL31661774 | 0.86 | TP53 (0.51) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL31661618 | 0.85 | HSD11B1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL31661564 | 0.84 | MEN1 (0.44) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL31661583 | 0.84 | S1PR1 (0.47) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL31661554 | 0.82 | SMN1; SMN2 (0.40) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL31661611 | 0.82 | NPC1 (0.41) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL25729010 | 0.81 | AMY1A (0.42) | ALDH1A1KDM4EHSD17B10HPGDPTGS1 | |
| SCHEMBL31661543 | 0.81 | S1PR1 (0.45) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL31661659 | 0.80 | LMNA (0.55) | NPC1RAB9AMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |