Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.47 |
| ▸ | USP1 | O94782 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661726 | 0.92 | USP1 (0.41) | S1PR1USP1SMN1; SMN2POLB | |
| SCHEMBL31661695 | 0.92 | S1PR1 (0.46) | S1PR1USP1SMN1; SMN2POLB | |
| SCHEMBL31661739 | 0.86 | NPC1 (0.36) | S1PR1SMN1; SMN2KDM4E | |
| SCHEMBL31661724 | 0.85 | USP1 (0.41) | S1PR1USP1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL31661494 | 0.84 | USP1 (0.42) | S1PR1USP1NPSR1SMN1; SMN2 | |
| SCHEMBL31661802 | 0.83 | NPC1 (0.43) | S1PR1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL31661583 | 0.82 | S1PR1 (0.47) | S1PR1USP1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL31661744 | 0.80 | NR1H4 (0.50) | S1PR1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL31661762 | 0.80 | NR1H4 (0.50) | S1PR1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL31661659 | 0.78 | LMNA (0.55) | S1PR1NPSR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |