Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661744 | 0.95 | NR1H4 (0.50) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661762 | 0.95 | NR1H4 (0.50) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661798 | 0.88 | CASP3 (0.44) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661653 | 0.86 | USP1 (0.52) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661677 | 0.86 | USP1 (0.52) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661764 | 0.84 | RAB9A (0.43) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661802 | 0.84 | NPC1 (0.43) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661587 | 0.84 | SMN1; SMN2 (0.56) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661753 | 0.83 | S1PR1 (0.42) | LMNATHRBS1PR1NPC1RAB9A | |
| SCHEMBL31661828 | 0.81 | USP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |