Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 10/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661659 | 0.88 | LMNA (0.55) | CASP3LMNATHRBS1PR1S1PR3 | |
| SCHEMBL31661753 | 0.84 | S1PR1 (0.42) | CASP3LMNATHRBS1PR1S1PR3 | |
| SCHEMBL31661762 | 0.83 | NR1H4 (0.50) | CASP3LMNATHRBS1PR1S1PR3 | |
| SCHEMBL31661744 | 0.83 | NR1H4 (0.50) | CASP3LMNATHRBS1PR1S1PR3 | |
| SCHEMBL25234699 | 0.81 | USP1 (0.40) | USP1DGAT1 | |
| SCHEMBL31661803 | 0.81 | USP1 (0.58) | USP1 | |
| SCHEMBL31661764 | 0.78 | RAB9A (0.43) | CASP3LMNATHRBS1PR1S1PR3 | |
| SCHEMBL31661698 | 0.77 | USP1 (0.38) | CASP3LMNATHRBS1PR1ALDH1A1 | |
| SCHEMBL31661802 | 0.76 | NPC1 (0.43) | LMNATHRBS1PR1S1PR3ALDH1A1 | |
| SCHEMBL31661587 | 0.76 | SMN1; SMN2 (0.56) | LMNATHRBS1PR1S1PR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |