Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241516 | 1.00 | DGAT1 (0.53) | DGAT1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL16074592 | 0.85 | DGAT1 (0.50) | DGAT1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL2132503 | 0.84 | DGAT1 (0.40) | DGAT1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL194112 | 0.82 | CES2 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3455630 | 0.80 | ESR1 (0.37) | DGAT1ALDH1A1 | |
| SCHEMBL20600120 | 0.80 | LOXL2 (0.40) | LMNASMN1; SMN2KMT2AHPGDKDM1A | |
| SCHEMBL13234347 | 0.79 | DGAT1 (0.45) | DGAT1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL16029046 | 0.79 | DGAT1 (0.45) | DGAT1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL4586556 | 0.78 | CYP11B2 (0.43) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1439041 | 0.78 | CRBN (0.37) | DGAT1LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |