SCHEMBL31661826

SCHEMBL31661826

NC(=O)c1sccc1-c1cncc(Br)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.54
CYP2A6 P11509 2/20 0.47
DAPK3 O43293 1/20 0.39
PRKD3 O94806 1/20 0.39
PIM1 P11309 1/20 0.39
PRKACA P17612 1/20 0.39
FLT1 P17948 1/20 0.39
LTK P29376 1/20 0.39
GRK5 P34947 1/20 0.39
KDR P35968 1/20 0.39
MAP2K2 P36507 1/20 0.39
MAPK8 P45983 1/20 0.39
CSNK1A1 P48729 1/20 0.39
CDK8 P49336 1/20 0.39
CLK2 P49760 1/20 0.39
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39
CDK7 P50613 1/20 0.39
CDK9 P50750 1/20 0.39
RPS6KA3 P51812 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31661861 0.82 BCAT2 (0.54) BCAT2DAPK3PRKD3PIM1PRKACA
SCHEMBL29922877 0.79 BCAT2 (0.66) BCAT2KDRMAPK8RAB9APOLB
SCHEMBL6669302 0.77 BCAT2 (0.68) BCAT2CYP2A6LIMK1CHEK2LMNA
SCHEMBL31661820 0.77 BCAT2 (0.58) BCAT2DAPK3PRKD3PIM1PRKACA
SCHEMBL6667283 0.74 BCAT2 (0.69) BCAT2CDK8CHEK2
SCHEMBL15267071 0.73 BCAT2 (0.54) BCAT2CSNK1A1DYRK1BRAB9ANPC1
SCHEMBL31661908 0.72 BCAT2 (0.53) BCAT2KDRCHEK2KDM4EGABRA1
SCHEMBL4445671 0.71 BCAT2 (1.00) BCAT2MAPK8GABRA1GABRG2GABRB3
SCHEMBL31561155 0.70 BCAT2 (0.47) BCAT2KDRMAPK8SMN1; SMN2POLB
SCHEMBL31661900 0.70 BCAT2 (0.57) BCAT2LIMK1CHEK2POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151311-A1 NICOTINAMIDE DERIVATIVES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-07-17 WO disclosed