SCHEMBL31661861

SCHEMBL31661861

NC(=O)c1sccc1-c1cncc(F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.54
PTGS1 P23219 1/20 0.40
CHEK2 O96017 3/20 0.40
DYRK1A Q13627 3/20 0.40
FGFR3 P22607 3/20 0.40
KDR P35968 3/20 0.40
PLK4 O00444 2/20 0.40
DAPK3 O43293 2/20 0.40
CDK1 P06493 2/20 0.40
PIM1 P11309 2/20 0.40
FGFR1 P11362 2/20 0.40
PRKACA P17612 2/20 0.40
CDK2 P24941 2/20 0.40
MAPK1 P28482 2/20 0.40
MAPK9 P45984 2/20 0.40
CSNK1D P48730 2/20 0.40
GSK3A P49840 2/20 0.40
GSK3B P49841 2/20 0.40
RPS6KA3 P51812 2/20 0.40
PLK1 P53350 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31661826 0.82 BCAT2 (0.54) BCAT2CHEK2KDRDAPK3PIM1
SCHEMBL27353967 0.78 BCAT2 (0.69) BCAT2PTGS1CYP3A4IKBKBCHUK
SCHEMBL6669302 0.77 BCAT2 (0.68) BCAT2CHEK2LIMK1MKNK2CYP3A4
SCHEMBL6667283 0.74 BCAT2 (0.69) BCAT2PTGS1CHEK2CDK2CDC7
SCHEMBL30338453 0.73 BCAT2 (0.54) BCAT2CHEK2DYRK1AFGFR3KDR
SCHEMBL31661908 0.72 BCAT2 (0.53) BCAT2CHEK2FGFR3KDRCDK2
SCHEMBL31661820 0.71 BCAT2 (0.58) BCAT2PTGS1CHEK2FGFR3KDR
SCHEMBL4445671 0.71 BCAT2 (1.00) BCAT2PTGS1MAPK8CYP3A4GABRA1
SCHEMBL31661900 0.70 BCAT2 (0.57) BCAT2PTGS1CHEK2LIMK1CHEK1
SCHEMBL15323302 0.70 BCAT2 (0.57) BCAT2PLK1AURKBAURKAAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151311-A1 NICOTINAMIDE DERIVATIVES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-07-17 WO disclosed