Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.54 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.43 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011605 | 0.79 | BCAT2 (0.59) | MKNK1MKNK2BCAT2LIMK1IKBKB | |
| SCHEMBL12495840 | 0.78 | BCAT2 (0.62) | BCAT2IKBKBNPC1RAB9AKDM4E | |
| SCHEMBL30424151 | 0.75 | BCAT2 (0.58) | BCAT2LIMK1IKBKBCHUKLMNA | |
| SCHEMBL1379791 | 0.75 | BCAT2 (0.58) | BCAT2LIMK1IKBKBCHUKLMNA | |
| SCHEMBL31661900 | 0.74 | BCAT2 (0.57) | MKNK1MKNK2BCAT2LIMK1IKBKB | |
| SCHEMBL31661857 | 0.73 | SIRT3 (0.50) | BCAT2LIMK1LMNACYP1A2CYP3A4 | |
| SCHEMBL4717953 | 0.72 | BCAT2 (0.64) | BCAT2LIMK1IKBKBCHUKLMNA | |
| SCHEMBL27576830 | 0.72 | BCAT2 (0.58) | BCAT2KDM4EALDH1A1POLB | |
| SCHEMBL6669302 | 0.72 | BCAT2 (0.68) | MKNK1MKNK2BCAT2LIMK1IKBKB | |
| SCHEMBL31469002 | 0.72 | MKNK1 (0.52) | MKNK1MKNK2P2RX7LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151311-A1 | NICOTINAMIDE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-07-17 | — | — | WO | disclosed |